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Single-Cell Co-expression Analysis Reveals Distinct Functional Modules, Co-regulation Mechanisms and Clinical Outcomes

Fig 5

Interchromosomal interactions are prevalent in single-cell co-expressed genes.

(A) The fraction of co-expressed gene pairs located in the same chromosomes. (B) Map of the co-expressed gene pairs. Each line represent a pair of co-expressed genes. The color of the lines indicates whether they are in the same chromosomes: purple (intrachromosomal), and gray (interchromosomal). (C) The fraction of co-expressed gene pairs located in the same topological domains. (D) The fraction of intrachromosomal and interchromosomal co-expression genes with chromosomal interactions.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1004892.g005