Early Characterization of the Severity and Transmissibility of Pandemic Influenza Using Clinical Episode Data from Multiple Populations
Fig 1
Transmissibility and severity of pandemic influenza.
a Relationship between the total number of individuals infected and the basic reproductive number R0. Arrows show the non-linear effect of a 20% reduction in transmission: at lower reproductive numbers, the same intervention is much more effective. b Severity pyramid for infectious disease. The strength of symptoms and ability to detect cases increases with each level in the pyramid. c Conceptual two-dimensional classification of pandemics in terms of basic reproductive number (R0) and severity (pC), illustrating the likely impact of interventions, depending on where the outbreak falls in this parameter space (see main text).