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Memory Storage Fidelity in the Hippocampal Circuit: The Role of Subregions and Input Statistics

Fig 3

Pattern separation in the DG with random input.

A: Pairwise correlation between stored patterns in CA3 as a function of pairwise correlation in EC with learning in DG (green), without (blue) and when the CA3 code is set up randomly (red). Regression lines are plotted, r values are shown in the upper left. B-D: Recall performance of the different simulations in CA3 (B), CA1 (C) and EC (D). Dashed lines are simulations where the recurrent connections in CA3 have been removed.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1004250.g003