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Memory Storage Fidelity in the Hippocampal Circuit: The Role of Subregions and Input Statistics

Fig 1

Model overview.

A: The four subregions EC, DG, CA3 and CA1 are modeled. a denotes the proportion of cells being active at any given time. Arrows indicate connectivity among regions. Black ones are random and fixed connections, green ones are plastic and adjusted during learning. The number next to the arrows show the number of connections one cell in the downstream region has with the up stream region. B-C: Distribution of spacings (B) and orientations (C) of the grid population in one environment. Colours indicate the modules. D-E: Four examples of grid cells (one from each module) (D) and two examples of LEC cells (E). The two rows show the firing map of the cells in two distinct environments.

Fig 1

doi: https://doi.org/10.1371/journal.pcbi.1004250.g001