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Laminar and Dorsoventral Molecular Organization of the Medial Entorhinal Cortex Revealed by Large-scale Anatomical Analysis of Gene Expression

Figure 4

Laminar and intralaminar organization of MEC defined by differential gene expression.

(A) Composite image shows high-intensity pixels for 6 exemplar genes with layer-specific expression. Pixels outside of the MEC and parasubicular region are made semitransparent. Images for the genes Dcc and Wfs1 were re-registered for a second time after manual pre-processing to improve the quality of registration for this figure. (B) Schematic showing a refined genomic atlas of the layers and borders of MEC. The region between layer III and V is the lamina dissecans (LD).

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1004032.g004