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The HIV Mutation Browser: A Resource for Human Immunodeficiency Virus Mutagenesis and Polymorphism Data

Figure 2

Overview of the distribution of mutation data across the HIV proteome.

(A) Barplot of the counts of (i) the number of articles describing mutations, (ii) the number of distinct mutations and (iii) the number of residues with mutation data in the database for each protein in the HIV proteome. (B) Barplot of the counts of the number of curated articles in the database describing mutagenesis experiments or polymorphisms for each residue mapped onto the HIV proteome/genome. (C) Reverse transcriptase p66 subunit with residues coloured by number of articles referring to them. Most highly cited residues are in contact with the nucleotides or are known drug resistance mutations. White denotes no papers, full red denotes 50 or more papers, colouring is linearly scaled between 0 and 50.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1003951.g002