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Lipid Clustering Correlates with Membrane Curvature as Revealed by Molecular Simulations of Complex Lipid Bilayers

Figure 1

Initial and final structures of the plasma membrane.

POPC is shown in light gray, POPE in red, Sph in green, GM3 in magenta, Chol in cyan, POPS in blue and PIP2 in yellow. (A) Side view of the plasma membrane at 5 µs. (B) View of the outer leaflet at 0 and 5 µs, with the GM3 cluster circled in the latter panel. (C) The inner leaflet at 0 and 5 µs.

Figure 1

doi: https://doi.org/10.1371/journal.pcbi.1003911.g001