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Mathematical Modeling of Bacterial Kinetics to Predict the Impact of Antibiotic Colonic Exposure and Treatment Duration on the Amount of Resistant Enterobacteria Excreted

Figure 4

Predicted total amounts of resistant enterobacteria excreted for various levels of fecal ciprofloxacin concentrations and treatment duration.

Total amounts excreted and fecal ciprofloxacin concentrations are expressed as a relative reduction from the clinically relevant dose (15 mg/kg/day).

doi: https://doi.org/10.1371/journal.pcbi.1003840.g004