Advertisement

< Back to Article

Axonal Noise as a Source of Synaptic Variability

Figure 3

Random variability of AP waveform in thin squid giant axon type axons of 3 diameters.

The subfigures display data for N>200 single APs triggered by identical stimuli and initial conditions in thin squid giant axon model. (A) Distribution of AP width and (B) AP height (red circle, 1×SD; dotted circle 3×SD). (C) Mean waveform of the AP at the proximal site. (D) Pairwise difference between an AP's shape at the proximal and the distal location. The average difference is plotted in thick black, while the light grey shaded area represents the 3×SD range. Grey lines represent sample traces plotted individually. (E) Fluctuations around the mean pairwise difference. The average difference is plotted in thick black (0 by definition), while the light grey shaded area represents the 3×SD range. Grey lines represent sample traces plotted individually.

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1003615.g003