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Finding Novel Molecular Connections between Developmental Processes and Disease

Figure 5

Expected results by tissue.

Density of enrichment of developmental gene sets (labels on the right) in major disease subtrees. Values are z-score normalized densities, computed as described in Methods. Darker squares indicate that a larger fraction of the disease terms in the MeSH category have significant enrichment () of genes in the indicated gene set. Expected connections appear approximately along the diagonal in the first 7 columns, and throughout the rightmost two columns.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1003578.g005