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Finding Novel Molecular Connections between Developmental Processes and Disease

Figure 4

Detailed view of part of the Nervous System Disease subtree, showing enrichment of bone development genes.

Links to dementia and Alzheimer's disease are shown. Significance of each node in the tree is represented by color; a gradient of shades of blue indicates p-values ranging from 0 (darkest blue) to 1.0 (white). Clicking on a node or selecting a set of nodes allows users to see, in the box in the upper right corner, the selected disease terms, p-values, and genes shared between those diseases and the developmental gene set.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1003578.g004