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Finding Novel Molecular Connections between Developmental Processes and Disease

Figure 3

Triangle view of disease enrichment for the bone development gene set.

Each triangle represents one of the 26 top-level categories in the MeSH disease forest. Each dot represents a disease node with significant enrichment of brain development genes. To clearly indicate the significance of relationships between diseases and the query gene set in these small images, we used two colors: light brown dots indicate , and darker brown dots, . Mousing over the dots reveals a pop-up of the disease term associated with that node (Alzheimer Disease is shown). Clicking on the category name leads to a detailed view of that tree.

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1003578.g003