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Optimal Schedules of Light Exposure for Rapidly Correcting Circadian Misalignment

Figure 5

Predicted optimal circadian phase and amplitude for all phase shifts.

The format is exactly the same as figure 4. Days −2 and −1 may be used as a legend associating a unique hue to each phase of the oscillator. Brightness is then used to represent amplitude, with white corresponding to zero amplitude [37]. The exact coloring, based on the state of the model variables, is shown in supplemental figure S3. Figure (A) shows the predicted phase and amplitude under the optimal schedules for resetting the clock when 10,000 lux light is available; (B) 1000 lux; (C) 500 lux; (D) 200 lux; (E) 100 lux.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1003523.g005