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Optimal Schedules of Light Exposure for Rapidly Correcting Circadian Misalignment

Figure 2

Polar phase-amplitude resetting maps corresponding to figure 1.

Circadian phase is plotted in degrees, with 0° corresponding to entrained CBTmin (before the schedule shift occurs), while amplitude is measured on the radius. A 6 hour advance would be indicated by a shift to 90°, a 12 hour shift to 180°, and a 6 hour delay to 270°. The sleep/dark region is indicated by the shaded regions on the PARMs. The timing of entrained CBTmin in the new time zone is indicated by the dotted line. Figures (A)–(G) correspond directly to figures 1A–1G, with each subplot displaying the process re-entrainment under one of the six schedules considered in figure 1. The phase and amplitude of predicted CBTmin (magenta triangles) are plotted in a one-to-one correspondence with the markers of figure 1. In other words, the markers and lines of figure 1 are simply re-plotted here in phase-amplitude space. As in figure 1, re-entrainment is plotted for 4 days before the schedule shift and for 14 days after.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1003523.g002