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Quantitative Protein Localization Signatures Reveal an Association between Spatial and Functional Divergences of Proteins

Figure 7

Divergence of protein subcellular localization is significantly associated with divergence of biological process but not molecular function.

Contingency tables showing the numbers of SL and DL-pairs with similar or dissimilar (A) biological processes or (B) molecular functions based on the SGD GOSlim annotations. Only duplicate pairs with both P-profiles and GOSlim annotations were considered. (Duplicate pairs with 75% or more matching functional annotations = “similar” BP or MF pairs, otherwise = “dissimilar” BP or MF pairs; P-values shown were obtained using two-sided Fisher's exact tests.)

Figure 7