A Dendritic Mechanism for Decoding Traveling Waves: Principles and Applications to Motor Cortex
(A) Exemplar dendritic current (red) and resulting somatic spike train (black) exhibiting irregular inter-spike intervals. The coefficient of variation (CV = 0.76) and irregularity (IR = 0.35) measures were both computed over a 30 second window. (B) Coefficient of variation of the inter-spike intervals versus firing rate. (C) Irregularity metric for the same data. Box plot (yellow) reproduces the observed irregularity of PTN inter-spike intervals in primary motor cortex  where the whiskers indicate the extrema.