Statistical Analysis of Molecular Signal Recording
Performance of continuous decoding to estimate randomly determined sequences of eight concentrations over 20 minutes of recording, as a function of experimental parameters. Solid lines are median estimation errors, and dashed lines are 95% confidence intervals. A) Varying numbers of templates, with the CMLF fixed at and , and using DNAP kinetic parameters. B) Varying CMLFs, with the number of templates fixed at 1000, and using DNAP kinetic parameters. C, D) Varying DNAP pausing parameters, with a fixed elongation time of 20 ms, a fixed CMLF of and , and 1000 and 100 templates, respectively.