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Statistical Analysis of Molecular Signal Recording

Figure 3

Varying numbers of templates, CMLFs, and DNAP parameters.

Performance of continuous decoding to estimate randomly determined sequences of eight concentrations over 20 minutes of recording, as a function of experimental parameters. Solid lines are median estimation errors, and dashed lines are 95% confidence intervals. A) Varying numbers of templates, with the CMLF fixed at and , and using DNAP kinetic parameters. B) Varying CMLFs, with the number of templates fixed at 1000, and using DNAP kinetic parameters. C, D) Varying DNAP pausing parameters, with a fixed elongation time of 20 ms, a fixed CMLF of and , and 1000 and 100 templates, respectively.

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1003145.g003