Distinct Types of Disorder in the Human Proteome: Functional Implications for Alternative Splicing
Figure 1
Comparison of disorder rates in the yeast and human proteomes.
The relative rates of flexible, constrained and non-conserved disorder in the human proteome are shown. Percentages of the different categories in A) yeast proteins without human orthologs, B) yeast proteins with human orthologs, C) human proteins without yeast orthologs, D) human proteins with yeast orthologs. The human proteome contains higher rates of flexible disorder than the yeast proteome. Proteins without yeast orthologs, which are presumably younger, have higher rates of disorder.