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Rampant Exchange of the Structure and Function of Extramembrane Domains between Membrane and Water Soluble Proteins

Figure 6

Training process of secondary structure element score to separate similar and dissimilar structure pairs between membrane and soluble proteins.

(a) Distribution of the ssea scores of the positive set (similar structures) and the negative set (dissimilar structures) of membrane and soluble proteins. (b) SSEA score to filter the positives and the negatives was set to 50. (c) Fraction of membrane protein sequences that have structural homology with soluble protein structures.

Figure 6

doi: https://doi.org/10.1371/journal.pcbi.1002997.g006