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The Timing and Targeting of Treatment in Influenza Pandemics Influences the Emergence of Resistance in Structured Populations

Figure 1

Final epidemic sizes depend on treatment levels and relative transmissibility.

Figure shows the final epidemic size for various treatment levels when wild-type and resistant strains have differing transmissibilities. Treatment is only preferable when the wild-type strain is more transmissible than the resistant strain (i.e.: ). Model details given in [2]. Parameters: , and , , and .

Figure 1