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Microbial Co-occurrence Relationships in the Human Microbiome

Figure 5

Related microbial niches as determined by associations spanning habitats at multiple human body sites.

Each node represents a body site, with edge width indicating significant cross-site correlations (randomization p<0.05, see Methods). Green edges show co-occurrence, red co-exclusion. Skin, vaginal, oral soft tissue, and tooth plaque moieties are apparent, with the gut and airways notably lacking significant interactions with other available body site niches. However, most relationships between microbial relative abundances occur specifically within, rather than between, individual body sites.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1002606.g005