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The Impact of Phenotypic Switching on Glioblastoma Growth and Invasion

Figure 1

Schematic describing the continuous time Markov process each cell is subject to.

A living glioma cell can be in either of two states, proliferating (P) or migrating (M), and transitions between the states with rates and respectively. A P-cell divides at rate while an M-cell moves with rate . Both cell types go into apoptosis and die with a constant rate .

Figure 1

doi: https://doi.org/10.1371/journal.pcbi.1002556.g001