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Coherent Conformational Degrees of Freedom as a Structural Basis for Allosteric Communication

Figure 8

Site-site communication in chaperons.

(A) Matrices DPQ and CPQ for GroEL-GroES complex. Equatorial, intermediate and apical domains are marked CE, CI, CA and TE, TI, TA for the cis and trans rings respectively. (B) Similar to (A) but for CCT. All 16 subunits have been divided into three subdomains, but there were only 13 ATP analogs bound to the crystal structure.

Figure 8