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Conflicting Biomedical Assumptions for Mathematical Modeling: The Case of Cancer Metastasis

Figure 2

Visualization of expert views about the importance of canonical metastatic stages within the actual process of metastasis.

While commenting on the suggested diagram (see Figures 1 and 2A), most experts were not confident that certain stages proposed are part of the metastatic process observed in the laboratory or clinic. Font size represents the number of experts voting for inclusion of the stage represented by the corresponding phrase. (A) The schematic that we presented to experts as canonical. (B–D) Subgroups of experts: PhDs only (B), MDs only (C), MD/PhDs (D). (E) The distribution of certainty across all experts.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1002132.g002