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deFuse: An Algorithm for Gene Fusion Discovery in Tumor RNA-Seq Data

Figure 3

Searching for candidate split reads.

a) Approximate fusion boundaries, shown as dashed rectangles, are the intersection of fusion boundary regions for discordant alignments supporting a potential fusion. b) The mate alignment region, shown as a dashed rectangle, is the union of possible alignment locations for the other end of a single end anchored alignment. c) The approximate fusion boundary in transcript is projected into transcript by remapping the start of the approximate fusion boundary from , to the genome, to .

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1001138.g003