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Deciphering the Code for Retroviral Integration Target Site Selection

Figure 5

Association (F score) between HIV-1 proviruses and two markers as a function of window size in kB.

The first marker is H3K4me3 sites in HeLa (green solid line). The second is a virtual marker placed in the promoter region of transcribed genes in HeLa cells (blue dashed line), assuming a uniform distribution of integration sites in transcribed regions. The median length of transcribed genes in HeLa is ∼20kB.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1001008.g005