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An Evolutionary Model-Based Algorithm for Accurate Phylogenetic Breakpoint Mapping and Subtype Prediction in HIV-1

Figure 5

Power and accuracy in the sequence shuffling simulation.

Power of SCUEAL to detect breakpoints in the HIV-1 pol sequence shuffling scenario as a function of recombinant fragment length (x-axis) and divergence between parental strains (y-axis). Grid cells are colored according to the proportion of correctly detected breakpoints (different cells may summarize different numbers of simulations). White squares are plotted when there were no simulated breakpoints within a corresponding length-divergence range of values.

Figure 5