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Global Motions of the Nuclear Pore Complex: Insights from Elastic Network Models

Figure 1

Schematic view of model adopted for the NPC/NE system.

The yeast NPC consists of 456 proteins (nucleoporins), shown here as spheres, that form eight identical spokes. The cytoplasmic face of the NPC (facing the viewer) is colored pink, and the nuclear face is colored light blue. A single spoke is highlighted in red/blue. The lumenal ring, consisting of sixteen POM152 nucleoporins is colored orange. Half of the NE fragment is shown in silver, and the border of the NE fragment is colored black.

Figure 1