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Statistical Methods for Detecting Differentially Abundant Features in Clinical Metagenomic Samples

Figure 1

Format of the feature abundance matrix.

Each row represents a specific taxon, while each column represents a subject or replicate. The frequency of the ith feature in the jth subject (c(i,j)) is recorded in the corresponding cell of the matrix. If there are g subjects in the first population, they are represented by the first g columns of the matrix, while the remaining columns represent subjects from the second population.

Figure 1