Formation and Growth of Oligomers: A Monte Carlo Study of an Amyloid Tau Fragment
Figure 3
Six snapshots from the aggregated phase of the 12-chain run at low concentration (side length 80 Å).
The snapshots (a)–(f) were taken after 67, 68, 71, 86, 91 and 96 steps, respectively. Side-chain colors are as in Figure 2. (a) A six-stranded β-sheet in contact with two random coils. (b) Two β-sheets with seven and two chains, respectively, and a random coil. (c) One eight- and one two-stranded β-sheet. (d) A nine-stranded β-sheet and a 310-helix. (e) One six- and one four-stranded β-sheet. (f) The same sheets as in (e) but with a different relative orientation.