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Biomedical Discovery Acceleration, with Applications to Craniofacial Development

Figure 6

Graph of top 1000 edges asserted by the combination of expression data and background biological knowledge.

Graph illustrating the network generated by taking the highest scoring 1000 edges as asserted by the Average (blue edges) and/or Logit (green edges) combinatorial measures. Blue edges indicate those edges asserted by both Average and Logit metrics. A total of 945 unique nodes (genes) and 1743 edges are shown (visualized in Cytoscape). The circled medium-sized sub-cluster to the right of the graph forms the basis of the investigations presented here (Figure 7).

Figure 6