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A Model of Brain Circulation and Metabolism: NIRS Signal Changes during Physiological Challenges

Figure 1

Summary of the main inputs, variables and processes in the model.

Model inputs are enclosed in solid ovals, while outputs are enclosed in dashed ovals. Pa is arterial blood pressure, SaO2 is arterial oxygen saturation level, PaCO2 is arterial CO2 level. TOS and ΔoxCCO are NIRS signals defined in the text.

Figure 1

doi: https://doi.org/10.1371/journal.pcbi.1000212.g001