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ChromaSig: A Probabilistic Approach to Finding Common Chromatin Signatures in the Human Genome

Figure 9

Overlap of genomewide clusters with known annotations.

Percentage of each cluster within 2.5-kb of (A) 21211 Refseq 5′ ends [23], (B) 20754 Refseq 3′ ends [23], (C) 95709 DNase I hypersensitive sites mapped in CD4+ T cells [29], and (D) 21959 regulatory sites from the ORegAnno database [30], as compared to 100 sets of random sites. (E) Distribution of maximum PhastCons scores [25] over a 1-kb window centered at ChromaSig aligned sites, as compared to 10000 random sites.

Figure 9