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ChromaSig: A Probabilistic Approach to Finding Common Chromatin Signatures in the Human Genome

Figure 3

Comparison of ChromaSig to a supervised clustering method from Heintzman et al. [15].

(A) Heatmaps (top) and average histone modification profiles (bottom) for cluster CS1, together with those for SP3 and SP4, which recover CS1 (33.3% recovery by SP3 and 31.1% recovery by SP4). (B) Heatmaps (top) and average histone modification profiles (bottom) for cluster CS2, together with those for SE3, which recovers CS2 (61.2% recovery by SE3). (C) Heatmaps (top) and average histone modification profiles (bottom) for cluster CS8, together with those for SE4, which recovers CS8 (26.5% recovery by SE4). The color of each curve is indicated by the color of the cluster label.

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1000201.g003