Advertisement

< Back to Article

Gene-Boosted Assembly of a Novel Bacterial Genome from Very Short Reads

Figure 1

Comparative assembly using multiple genomes.

The target genome is shown in the center, aligned to two related genomes, A and B. The DNA sequence of the target diverges from the reference genomes in distinct loci, labeled X, Y, and Z. The comparative assembly based on genome A contains a gap corresponding to region Y, while the assembly based on genome B contains two gaps, corresponding to X and Z. The merged assembly will cover all of the target genome with no gaps.

Figure 1

doi: https://doi.org/10.1371/journal.pcbi.1000186.g001