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Predicting and Validating Protein Interactions Using Network Structure

Figure 1

Upcast Sets of Characteristic Pairs and Triplets.

In this example, we consider only a single characteristic (e.g., protein function), so that the characteristic vector for a protein is a 1-vector. There are three single-category proteins and one two-category protein in the protein interaction network (left), which result in an upcast set of six characteristic pairs {AB, AB, AD, BD, BC, CD}. Alternatively, the upcast set of triplets includes two triangles and three lines.

Figure 1

doi: https://doi.org/10.1371/journal.pcbi.1000118.g001