Advertisement

< Back to Article

Functional Maps of Protein Complexes from Quantitative Genetic Interaction Data

Figure 4

Aggravating complexes are more likely to contain essential genes.

The percentage of complexes that contain at least one essential gene is shown, for various groups of complexes defined within small-scale complexes in MIPS (left three bars) or complexes identified in this study (right three bars). In MIPS, approximately 80% of “aggravating” complexes (see text) contain an essential gene, versus 20% for “alleviating” complexes. The trend is similar for the complexes reported in this study, with 55% versus 22% of aggravating versus alleviating complexes containing an essential gene. The list of all essential genes was taken from (http://www-sequence.stanford.edu/group/yeast_deletion_project/deletions3.html).

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1000065.g004