Advertisement

< Back to Article

Sequence Similarity Network Reveals Common Ancestry of Multidomain Proteins

Figure 1

The evolution of a hypothetical multidomain family by gene duplication and domain insertion.

Genes in the a and b subfamilies share a common ancestor but do not have identical domain composition. Gene c shares a homologous domain with genes in the b subfamily, but there is no gene that is ancestral to both b and c.

Figure 1

doi: https://doi.org/10.1371/journal.pcbi.1000063.g001