The Carbon Assimilation Network in Escherichia coli Is Densely Connected and Largely Sign-Determined by Directions of Metabolic Fluxes

Open Access

Peer-reviewed

Research Article

Valentina Baldazzi,

Affiliation Institut National de Recherche en Informatique et en Automatique, INRIA Grenoble - Rhône-Alpes, Montbonnot, France
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Delphine Ropers,

Affiliation Institut National de Recherche en Informatique et en Automatique, INRIA Grenoble - Rhône-Alpes, Montbonnot, France
⨯
Yves Markowicz,

Affiliations Institut National de Recherche en Informatique et en Automatique, INRIA Grenoble - Rhône-Alpes, Montbonnot, France, Laboratoire Adaptation et Pathogénie des Microorganismes (CNRS UMR 5163), Université Joseph Fourier, Bâtiment Jean Roget, Faculté de Médecine-Pharmacie, La Tronche, France
⨯
Daniel Kahn,

Affiliations Institut National de Recherche en Informatique et en Automatique, INRIA Grenoble - Rhône-Alpes, Montbonnot, France, Laboratoire de Biométrie et Biologie Evolutive (CNRS UMR 5558), Université Lyon 1, INRA, Villeurbanne, France
⨯
Johannes Geiselmann,

Affiliations Institut National de Recherche en Informatique et en Automatique, INRIA Grenoble - Rhône-Alpes, Montbonnot, France, Laboratoire Adaptation et Pathogénie des Microorganismes (CNRS UMR 5163), Université Joseph Fourier, Bâtiment Jean Roget, Faculté de Médecine-Pharmacie, La Tronche, France
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Hidde de Jong

* E-mail: Hidde.de-Jong@inria.fr

Affiliation Institut National de Recherche en Informatique et en Automatique, INRIA Grenoble - Rhône-Alpes, Montbonnot, France
⨯

Reader Comments

Schematic illustration of the four sufficient conditions for sign determinedness, C1–C4.
http://ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000812#pcbi-1000812-g002

The equations below the legend of Figure 2 are not part of the Figure 2 legend.

No competing interests declared.

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