Functional Impact of Missense Variants in BRCA1 Predicted by Supervised Learning

• Rachel Karchin ,

  *To whom correspondence should be addressed. E-mail: karchin@karchinlab.org (RK); sali@salilab.org (AS)

  Affiliations Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America , Institute of Computational Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Alvaro N. A Monteiro,

  Affiliation Risk Assessment, Detection, and Intervention Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America

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• Sean V Tavtigian,

  Affiliation International Agency for Research on Cancer, Lyon, France

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• Marcelo A Carvalho,

  Affiliation Risk Assessment, Detection, and Intervention Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America

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• Andrej Sali

  *To whom correspondence should be addressed. E-mail: karchin@karchinlab.org (RK); sali@salilab.org (AS)

  Affiliations Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America , California Institute for Quantitative Biomedical Research, University of California San Francisco, San Francisco, California, United States of America

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