Harvesting Candidate Genes Responsible for Serious Adverse Drug Reactions from a Chemical-Protein Interactome

Lun Yang; Jian Chen; Lin He

doi:10.1371/journal.pcbi.1000441

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Open Access

Peer-reviewed

Research Article

Harvesting Candidate Genes Responsible for Serious Adverse Drug Reactions from a Chemical-Protein Interactome

Lun Yang ,

* E-mail: lunyang@gmail.com (LY); helinhelin@gmail.com (LH)

Affiliations Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China, Institute of Biomedical Sciences, Fudan University, Shanghai, China
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Jian Chen,

Affiliation Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China
⨯
Lin He

* E-mail: lunyang@gmail.com (LY); helinhelin@gmail.com (LH)

Affiliations Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China, Institute of Biomedical Sciences, Fudan University, Shanghai, China, Institute for Nutritional Sciences, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai, China
⨯

Harvesting Candidate Genes Responsible for Serious Adverse Drug Reactions from a Chemical-Protein Interactome

Lun Yang,
Jian Chen,
Lin He

Published: July 24, 2009
https://doi.org/10.1371/journal.pcbi.1000441

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A good piece of work on the methodology and mechanism of the adverse drug reaction

Posted by Felico on 02 Sep 2009 at 22:59 GMT

This work provides a good insight into the mechanism of adverse drug reaction. The authors recovered some of the successful ADR stories, however, the experimental validations are still needed.

No competing interests declared.

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Harvesting Candidate Genes Responsible for Serious Adverse Drug Reactions from a Chemical-Protein Interactome

Harvesting Candidate Genes Responsible for Serious Adverse Drug Reactions from a Chemical-Protein Interactome

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A good piece of work on the methodology and mechanism of the adverse drug reaction

Posted by Felico on 02 Sep 2009 at 22:59 GMT