About the Authors

Roland Keller

Contributed equally to this work with: Roland Keller, Marcus Klein

Affiliation Center for Bioinformatics Tuebingen (ZBIT), University of Tuebingen, Tuebingen, Germany

Marcus Klein

Contributed equally to this work with: Roland Keller, Marcus Klein

Affiliations Dr. Margarete Fischer Bosch-Institute of Clinical Pharmacology, Stuttgart, University of Tuebingen, Tuebingen, Germany

Maria Thomas

Affiliations Dr. Margarete Fischer Bosch-Institute of Clinical Pharmacology, Stuttgart, University of Tuebingen, Tuebingen, Germany

Andreas Dräger

Affiliations Center for Bioinformatics Tuebingen (ZBIT), University of Tuebingen, Tuebingen, Germany, Systems Biology Research Group, University of California, San Diego, La Jolla, California, United States of America

Ute Metzger

Affiliation NMI Institute of Natural and Medical Sciences, Reutlingen, Germany

Markus F. Templin

Affiliation NMI Institute of Natural and Medical Sciences, Reutlingen, Germany

Thomas O. Joos

Affiliation NMI Institute of Natural and Medical Sciences, Reutlingen, Germany

Wolfgang E. Thasler

Affiliation Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Hospital of the University of Munich, Munich, Germany

Andreas Zell

Affiliation Center for Bioinformatics Tuebingen (ZBIT), University of Tuebingen, Tuebingen, Germany

Ulrich M. Zanger

uli.zanger@ikp-stuttgart.de

Affiliations Dr. Margarete Fischer Bosch-Institute of Clinical Pharmacology, Stuttgart, University of Tuebingen, Tuebingen, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MK MT UM MFT TOJ UMZ. Performed the experiments: MK MT UM MFT. Analyzed the data: RK MK MT UM MFT UMZ. Contributed reagents/materials/analysis tools: WET. Wrote the paper: RK MK MT AD AZ UMZ. Conducted modeling: RK AD AZ.