About the Authors

Jasmine Foo

Contributed equally to this work with: Jasmine Foo, Lin L Liu

Affiliation Department of Mathematics, University of Minnesota Twin Cities, St. Paul, Minnesota, United States of America

Lin L Liu

Contributed equally to this work with: Jasmine Foo, Lin L Liu

Affiliation Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, and Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, United States of America

Kevin Leder

Affiliation Industrial and Systems Engineering, University of Minnesota Twin Cities, St. Paul, Minnesota, United States of America

Markus Riester

Affiliation Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, and Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, United States of America

Yoh Iwasa

Affiliation Department of Biology, Kyushu University, Fukuoka, Japan

Christoph Lengauer

Affiliation Blueprint Medicines, Cambridge, Massachusetts, United States of America

Franziska Michor

michor@jimmy.harvard.edu

Affiliation Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, and Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, United States of America

Competing Interests

CL is affiliated with Blueprint Medicines, Cambridge, MA, USA. The other authors declare that no further competing interests exist.

Author Contributions

Conceived and designed the experiments: JF KL LLL MR YI CL FM. Performed the experiments: JF KL LLL MR. Analyzed the data: JF KL LLL MR FM. Contributed reagents/materials/analysis tools: JF KL LLL MR YI FM. Wrote the paper: JF KL LLL MR YI CL FM.