About the Authors

Jinyu Li

Affiliations Computational Biophysics, German Research School for Simulation Sciences (joint venture of RWTH Aachen University and Forschungszentrum Jülich, Germany), Jülich, Germany and Computational Biomedicine, Institute for Advanced Simulation IAS-5 and Institute of Neuroscience and Medicine INM-9, Forschungszentrum Jülich, Jülich, Germany, Institute of Biochemistry and Molecular Biology, RWTH Aachen University, Aachen, Germany

Giulia Rossetti

g.rossetti@grs-sim.de

Affiliations Computational Biophysics, German Research School for Simulation Sciences (joint venture of RWTH Aachen University and Forschungszentrum Jülich, Germany), Jülich, Germany and Computational Biomedicine, Institute for Advanced Simulation IAS-5 and Institute of Neuroscience and Medicine INM-9, Forschungszentrum Jülich, Jülich, Germany, Jülich Supercomputing Centre (JSC), Forschungszentrum Jülich, Jülich, Germany

Jens Dreyer

Affiliation Computational Biophysics, German Research School for Simulation Sciences (joint venture of RWTH Aachen University and Forschungszentrum Jülich, Germany), Jülich, Germany and Computational Biomedicine, Institute for Advanced Simulation IAS-5 and Institute of Neuroscience and Medicine INM-9, Forschungszentrum Jülich, Jülich, Germany

Simone Raugei

Affiliation Fundamental and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, Washington, United States of America

Emiliano Ippoliti

Affiliation Computational Biophysics, German Research School for Simulation Sciences (joint venture of RWTH Aachen University and Forschungszentrum Jülich, Germany), Jülich, Germany and Computational Biomedicine, Institute for Advanced Simulation IAS-5 and Institute of Neuroscience and Medicine INM-9, Forschungszentrum Jülich, Jülich, Germany

Bernhard Lüscher

Affiliation Institute of Biochemistry and Molecular Biology, RWTH Aachen University, Aachen, Germany

Paolo Carloni

Affiliation Computational Biophysics, German Research School for Simulation Sciences (joint venture of RWTH Aachen University and Forschungszentrum Jülich, Germany), Jülich, Germany and Computational Biomedicine, Institute for Advanced Simulation IAS-5 and Institute of Neuroscience and Medicine INM-9, Forschungszentrum Jülich, Jülich, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JL GR JD SR PC. Performed the experiments: JL GR JD SR EI. Analyzed the data: JL GR JD SR EI BL PC. Contributed reagents/materials/analysis tools: JL GR JD SR EI. Wrote the paper: JL GR JD SR EI BL PC.