About the Authors

Nobuto Takeuchi, Eugene V. Koonin
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

Paulien Hogeweg
Theoretical Biology and Bioinformatics Group, Utrecht University, Utrecht, The Netherlands

Corresponding Author

takeuchi@ncbi.nlm.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NT PH. Performed the experiments: NT. Analyzed the data: NT. Contributed reagents/materials/analysis tools: NT. Wrote the manuscript: NT PH EVK. Interpreted the results: NT PH EVK.