About the Authors

Katarzyna A. Rejniak

Kasia.Rejniak@moffitt.org

Affiliations Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America, Department of Oncologic Sciences, University of South Florida College of Medicine, Tampa, Florida, United States of America

Shizhen E. Wang

Affiliation Division of Tumor Cell Biology, Beckman Research Institute of City of Hope, Duarte, California, United States of America

Nicole S. Bryce

Address Current address: School of Chemistry, University of Sydney, Sydney, Australia

Affiliation Vanderbilt Integrative Cancer Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Hang Chang

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

Bahram Parvin

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

Jerome Jourquin

Affiliation Vanderbilt Integrative Cancer Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Lourdes Estrada

Affiliation Vanderbilt Integrative Cancer Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Joe W. Gray

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

Carlos L. Arteaga

Affiliation Vanderbilt Integrative Cancer Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Alissa M. Weaver

Affiliation Vanderbilt Integrative Cancer Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Vito Quaranta

Contributed equally to this work with: Vito Quaranta, Alexander R. A. Anderson

Affiliation Vanderbilt Integrative Cancer Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Alexander R. A. Anderson

Contributed equally to this work with: Vito Quaranta, Alexander R. A. Anderson

Affiliation Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SEW NSB LE CLA AMW VQ. Performed the experiments: SEW NSB. Analyzed the data: KAR HC BP JJ. Contributed reagents/materials/analysis tools: BP JWG CLA AMW VQ. Wrote the paper: KAR VQ ARAA. Conceived and designed the computational model: KAR ARAA. Performed computational simulations: KAR.