About the Authors

Enrico Petretto, Leonardo Bottolo, Sarah R. Langley, Chris McDermott-Roe, Rizwan Sarwar, Timothy J. Aitman, Stuart A. Cook
Medical Research Council Clinical Sciences Centre, Faculty of Medicine, Imperial College London, London, United Kingdom

Enrico Petretto, Leonardo Bottolo, Sylvia Richardson
Department of Epidemiology and Biostatistics, Faculty of Medicine, Imperial College, London, United Kingdom

Matthias Heinig, Norbert Hübner
Max-Delbrück Center for Molecular Medicine, Berlin, Germany

Michal Pravenec
Institute of Physiology, Czech Academy of Sciences and Centre for Applied Genomics, Prague, Czech Republic

Michal Pravenec
Charles University in Prague, Institute of Biology and Medical Genetics of the First Faculty of Medicine and General Teaching Hospital, Prague, Czech Republic

Timothy J. Aitman
Section of Molecular Genetics and Rheumatology, Division and Faculty of Medicine, Imperial College, London, United Kingdom

Stuart A. Cook
National Heart and Lung Institute, Imperial College, London, United Kingdom

Corresponding Author

sylvia.richardson@imperial.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Designed the study: EP LB. Developed the code for the SBR and SBMR analyses: LB. Performed all statistical analyses: EP LB SRL. Performed all PCR based experiments: CMR RS SAC. Contributed reagents and materials for the study: MH MP NH TJA SAC. Wrote the paper: EP LB SR.