About the Authors

Wesley C. Van Voorhis
Department of Medicine, University of Washington, Seattle, Washington, United States of America

Wim G. J. Hol
Department of Biochemistry, University of Washington, Seattle, Washington, United States of America

Peter J. Myler
Seattle Biomedical Research Institute, Seattle, Washington, United States of America

Peter J. Myler
Department of Global Health, University of Washington, Seattle, Washington, United States of America

Peter J. Myler
Department of Medical Education and Biomedical Informatics, University of Washington, Seattle, Washington, United States of America

Lance J. Stewart
deCODE biostructures, Bainbridge Island, Washington, United States of America

Corresponding Authors

Competing Interests

Co-author Lance Stewart is an employee of deCODE biostructures, which developed the Fragments-of-Life library presented in Figure 1 and discussed in sections titled ‘Fragment-based drug discovery’ and ‘Targeting oligomeric enzymes’. Fragments-of-Life TM is a technology trademarked by deCODE biostructures and chemistry (http://www.decodechembio.com/Capabilities/StructuralBiology/FragmentsofLife.aspx).