About the Authors

James Corey Adams
Graduate Program in Pharmaceutical Sciences and Pharmacogenomics, University of California, San Francisco, California, United States of America

Michael J. Keiser
Graduate Program in Bioinformatics, University of California, San Francisco, California, United States of America

Li Basuino, Henry F. Chambers
San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America

Deok-Sun Lee
Center for Complex Network Research and Departments of Physics, Biology, and Computer Science, Northeastern University, Boston, Massachusetts, United States of America

Deok-Sun Lee
Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

Deok-Sun Lee
Department of Natural Medical Sciences, Inha University, Incheon, Korea

Olaf G. Wiest
Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, United States of America

Patricia C. Babbitt
Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California, United States of America

Patricia C. Babbitt
Department of Pharmaceutical Chemistry, University of California, San Francisco, California, United States of America

Patricia C. Babbitt
California Institute for Quantitative Biosciences, University of California, San Francisco, California, United States of America

Corresponding Author

Babbitt@cgl.ucsf.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JCA MJK OGW PCB. Performed the experiments: JCA MJK LB. Analyzed the data: JCA OGW. Contributed reagents/materials/analysis tools: MJK D-SL HFC. Wrote the paper: JCA PCB.