About the Authors

Tom C Freeman
Division of Pathway Medicine, University of Edinburgh Medical School, Edinburgh, United Kingdom

Tom C Freeman, Markus Brosch, Stijn van Dongen, Pierre Mazière, Russell J Grocock, Anton J Enright
Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

Leon Goldovsky, Shiri Freilich, Janet Thornton
European Bioinformatics Institute, Hinxton, Cambridge, United Kingdom

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

TCF and AJE conceived and designed the experiments and wrote the paper. TCF, LG, SvD, and AJE performed the experiments. All authors analyzed the data. TCF, LG, MB, SvD, SF, JT, and AJE contributed reagents/materials/analysis tools.